CHD8 Antikörper (AA 325-350)
Kurzübersicht für CHD8 Antikörper (AA 325-350) (ABIN7453579)
Target
Alle CHD8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 325-350
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Verwendungszweck
- Rabbit anti-CHD8 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 325 and 350
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))
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Andere Bezeichnung
- CHD8
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Hintergrund
- Background: CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.
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Gen-ID
- 57680
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NCBI Accession
- NP_065971
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UniProt
- Q9HCK8
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Pathways
- Chromatin Binding
Target
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