GIT2 Antikörper (AA 500-550)

Produktnummer ABIN7453500

Dieser Anti-GIT2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GIT2 in WB, IP und IHC (fp). Geeignet für Human.

Kurzübersicht für GIT2 Antikörper (AA 500-550) (ABIN7453500)

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-GIT2 Antikörper

Bindungsspezifität: AA 500-550

Verwendungszweck: Rabbit anti-GIT2 Antibody, Affinity Purified

Homologie: Mouse

Aufreinigung: Affinity Purified

Immunogen: between AA 500 and 550

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-GIT2 antibody ABIN7451796.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu GIT2

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Andere Bezeichnung: GIT2

Hintergrund: Background: G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules.

Gen-ID: 9815

NCBI Accession: NP_476510

UniProt: Q14161

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling