BCR Antikörper (AA 1221-1271)
Kurzübersicht für BCR Antikörper (AA 1221-1271) (ABIN7453394)
Target
Alle BCR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1221-1271
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Verwendungszweck
- Rabbit anti-BCR Antibody, Affinity Purified
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Homologie
- Mouse
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1221 and 1271
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Isotyp
- IgG
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Applikationshinweise
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ICC-IF: 1:500 - 1:2,000
IP: 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- BCR (Breakpoint Cluster Region (BCR))
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Andere Bezeichnung
- BCR
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Hintergrund
- Background: BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.
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Gen-ID
- 613
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NCBI Accession
- NP_004318
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UniProt
- P11274
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Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
Target
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