DDIT4 Antikörper (AA 1-50)
Kurzübersicht für DDIT4 Antikörper (AA 1-50) (ABIN7453391)
Target
Alle DDIT4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-REDD1 Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Bovine,Dog,Horse,Rabbit,Panda,Orangutan,Monkey,Gorilla,Chimpanzee
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1 and 50
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Isotyp
- IgG
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Applikationshinweise
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ICC-IF: 1:500 - 1:2,000. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.
IP: 5 - 15 μg/mg lysate
WB: 1:1,000 - 1:4,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
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Andere Bezeichnung
- REDD1
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Hintergrund
- Background: REDD1 (regulated in development and DNA damage response 1) is a direct transcriptional target of HIF. It plays a role in the TSC/mTOR pathway as a regulator upstream of the TSC1/2 complex. In response to both hypoxia and energy stress, REDD1 inhibits mTOR activity in a TSC-dependent manner. Alternative names for REDD1 include DDIT4, DNA-damage-inducible transcript 4 protein, and RTP801.
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Gen-ID
- 54541
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NCBI Accession
- NP_061931
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UniProt
- Q9NX09
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Pathways
- Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process
Target
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