Treslin Antikörper (AA 975-1025)

Produktnummer ABIN7453283

Produktdetails anti-Treslin Antikörper

Target: Treslin

Bindungsspezifität: AA 975-1025

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Treslin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit anti-Treslin Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 975 and 1025

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: Not recommended

WB: 1:500 - 1:2,500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Treslin

Target: Treslin

Abstract: Treslin Produkte

Synonyme: C15orf42 antikoerper, SLD3 antikoerper, Treslin antikoerper, 5730590G19Rik antikoerper, BC028450 antikoerper, Lrrk1 antikoerper, c15orf42 antikoerper, TOPBP1 interacting checkpoint and replication regulator antikoerper, TopBP1-interacting, checkpoint, and replication regulator antikoerper, TOPBP1-interacting checkpoint and replication regulator antikoerper, TOPBP1-interacting checkpoint and replication regulator L homeolog antikoerper, TICRR antikoerper, ticrr antikoerper, Ticrr antikoerper, ticrr.L antikoerper

Hintergrund: Background: Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) Q7Z2Z1].

Gen-ID: 90381

NCBI Accession: NP_689472

UniProt: Q7Z2Z1