ARVCF Antikörper (AA 75-125)

Produktnummer ABIN7453257

Der Kaninchen Polyklonal anti-ARVCF Antikörper (ABIN7453257) detektiert spezifisch ARVCF in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ARVCF Antikörper (AA 75-125) (ABIN7453257)

Target: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARVCF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARVCF Antikörper

Bindungsspezifität: AA 75-125

Verwendungszweck: Rabbit anti-ARVCF Antibody, Affinity Purified

Homologie: Mouse

Aufreinigung: Affinity Purified

Immunogen: between AA 75 and 125

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: Not recommended

WB: 1:500 - 1:2,500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ARVCF

Target: ARVCF (Armadillo Repeat Gene Deleted in Velocardiofacial Syndrome (ARVCF))

Andere Bezeichnung: ARVCF

Hintergrund: Background: Armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein [taken from NCBI Entrez Gene (Gene ID: 421)].

Gen-ID: 421

NCBI Accession: NP_001661

UniProt: O00192