IDE Antikörper (AA 275-326)
Kurzübersicht für IDE Antikörper (AA 275-326) (ABIN7453106)
Target
Alle IDE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 275-326
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Verwendungszweck
- Rabbit anti-IDE Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 275 and 326
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Isotyp
- IgG
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Applikationshinweise
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- IDE (Insulin-Degrading Enzyme (IDE))
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Andere Bezeichnung
- IDE
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Hintergrund
- Background: Insulin-degrading enzyme (IDE) is a metalloendopeptidase that plays a primary role in the regulated degradation of insulin. In the cell, IDE is found mostly in the soluble cytosolic fraction, and small amounts exist in the plasma membrane, endosomes, and peroxisomes, however the highest relative concentration is found in the peroxisomes. IDE is proposed to be a multifunctional enzyme since it is also present in non-insulin sensitive cells. Other substrates of IDE include glucagon, IGF-II, atrial natriuretic factor, and TGF-alpha.
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Gen-ID
- 3416
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NCBI Accession
- NP_004960
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UniProt
- P14735
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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