ASCC1 Antikörper (AA 1-50)

Produktnummer ABIN7452923

Der Kaninchen Polyklonal Anti-ASCC1-Antikörper wurde für WB validiert. Er ist geeignet, ASCC1 in Proben von Human zu detektieren.

Kurzübersicht für ASCC1 Antikörper (AA 1-50) (ABIN7452923)

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ASCC1 Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Rabbit anti-ASCC1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 1 and 50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: Not recommended

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ASCC1

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Andere Bezeichnung: ASCC1

Hintergrund: Background: Activating signal cointegrator 1 complex subunit 1 (ASCC1) is a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). ASCC1 contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in the ASCC1 gene are associated with Barrett esophagus and esophageal adenocarcinoma [taken from NCBI Entrez Gene (Gene ID: 51008)].

Gen-ID: 51008

NCBI Accession: NP_001185728

UniProt: Q8N9N2