C17ORF85 Antikörper (AA 25-75)

Produktnummer ABIN7452805

Produktdetails anti-C17ORF85 Antikörper

Target: C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))

Bindungsspezifität: AA 25-75

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C17ORF85 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-C17orf85 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 25 and 75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu C17ORF85

Target: C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))

Andere Bezeichnung: C17orf85 (C17ORF85 Produkte)

Synonyme: ELG antikoerper, HSA277841 antikoerper, C130061O14Rik antikoerper, C78393 antikoerper, nuclear cap binding subunit 3 antikoerper, nuclear cap binding subunit 3 L homeolog antikoerper, NCBP3 antikoerper, Ncbp3 antikoerper, ncbp3.L antikoerper

Hintergrund: Background: C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) Q53F19].

Gen-ID: 55421

UniProt: Q53F19