POLA2 Antikörper (AA 448-498)
Kurzübersicht für POLA2 Antikörper (AA 448-498) (ABIN7452745)
Target
Alle POLA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 448-498
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Verwendungszweck
- Rabbit anti-PolA2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 448 and 498
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Isotyp
- IgG
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Applikationshinweise
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IP: 5 - 15 μg/mg lysate
WB: 1:1,000 - 1:5,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- POLA2 (Polymerase (DNA Directed), alpha 2 (70kD Subunit) (POLA2))
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Andere Bezeichnung
- PolA2
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Hintergrund
- Background: DNA polymerase alpha is a four-subunit enzyme that exhibits DNA polymerase and primase activity. The four subunits of the heterotetrameric DNA pol alpha are A, B, C, and D. Subunit A displays the catalytic activity while the C and D subunits exhibit the primase activity. DNA polymerase (pol) alpha subunit B (PolA2) is the 70 kDa subunit that may serve to couple the DNA pol alpha-primase complex to the initiation/elongation machinery. DNA pol alpha is the only polymerase in eukaryotic cells that is capable of starting chains de novo.
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Gen-ID
- 23649
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NCBI Accession
- NP_002680
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UniProt
- Q14181
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Pathways
- Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Protein targeting to Nucleus, Synthesis of DNA, SARS-CoV-2 Protein Interaktom
Target
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