BUB1B Antikörper (AA 350-400)
Kurzübersicht für BUB1B Antikörper (AA 350-400) (ABIN7452565)
Target
Alle BUB1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 350-400
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Verwendungszweck
- Rabbit anti-BubR1 Antibody, Affinity Purified
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Homologie
- Panda,Orangutan,Monkey,Gorilla
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 350 and 400
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Isotyp
- IgG
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Applikationshinweise
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IP: 2- 10 μg/mg lysate
WB: 1:2,000 - 1:15,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
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Andere Bezeichnung
- BubR1
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Hintergrund
- Background: BubR1 is cell cycle checkpoint kinase and component of the spindle checkpoint machinery. BubR1 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. BubR1 is part of the mitotic checkpoint complex that also includes Bub3, Mad2, and Cdc20. In this trimer BubR1 functions to inhibit the anaphase promoting complex (APC) that promotes chromosome segregation. BubR1 is suggested to be a paralog of Bub1.
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Gen-ID
- 701
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UniProt
- O60566, Q8WV50
Target
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