KIDINS220 Antikörper (AA 1721-1771)

Produktnummer ABIN7452488

Produktdetails anti-KIDINS220 Antikörper

Target: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Bindungsspezifität: AA 1721-1771

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIDINS220 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-ARMS Antibody, Affinity Purified

Homologie: Rat

Aufreinigung: Affinity Purified

Immunogen: between AA 1721 and 1771

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu KIDINS220

Target: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Andere Bezeichnung: ARMS (KIDINS220 Produkte)

Synonyme: ARMS antikoerper, fj35h03 antikoerper, kidins220 antikoerper, zgc:63531 antikoerper, dZ119J18.2 antikoerper, wu:fj35h03 antikoerper, 3110039L19Rik antikoerper, AI194387 antikoerper, AI316525 antikoerper, C330002I19Rik antikoerper, mKIAA1250 antikoerper, kinase D interacting substrate 220 antikoerper, kinase D-interacting substrate 220 antikoerper, kinase D-interacting substrate 220b antikoerper, kinase D-interacting substrate 220kDa antikoerper, KIDINS220 antikoerper, Kidins220 antikoerper, kidins220b antikoerper

Hintergrund: Background: Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) Q9ULH0].

Gen-ID: 57498

NCBI Accession: NP_065789

UniProt: Q9ULH0