Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 2150-2200) Antikörper
Kurzübersicht für Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 2150-2200) Antikörper (ABIN7452441)
Target
Alle Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2150-2200
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Verwendungszweck
- Rabbit anti-SPTBN2/SCA5 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 2150 and 2200
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-SPTBN2/SCA5 antibody ABIN7450766.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
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Andere Bezeichnung
- SPTBN2/SCA5
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Hintergrund
- Background: SPTBN2/SCA5 is a member of the beta spectrin gene family and a subunit of the spectrin cytoskeletal scaffolding protein that links the plasma membrane to cytoskeletal actin and functions in cellular shape and organelle organization. SPTBN2/SCA5 has been identified as a Golgi- and vesicle-associated spectrin. Mutations in SPTBN2/SCA5 cause spinocerebellar ataxia type 5 (SCA5), an autosomal dominant disease characterized by progressive incoordination of gait, hand, speech, and eye movements.
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Gen-ID
- 6712
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NCBI Accession
- NP_008877
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UniProt
- O15020
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Pathways
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
Target
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