SIRT6 Antikörper (AA 50-100)
Kurzübersicht für SIRT6 Antikörper (AA 50-100) (ABIN7452433)
Target
Alle SIRT6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 50-100
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Verwendungszweck
 - Rabbit anti-Sirt6 Antibody, Affinity Purified
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Homologie
 - Mouse
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Aufreinigung
 - Affinity Purified
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Immunogen
 - between AA 50 and 100
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Isotyp
 - IgG
 
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-Sirt6 antibody ABIN7451598.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 1000 μg/mL
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Buffer
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C
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Haltbarkeit
 - 12 months
 
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- SIRT6 (Sirtuin 6 (SIRT6))
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Andere Bezeichnung
 - Sirt6
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Hintergrund
 - Background: Sirtuin 6 (Sirt6) is a NAD-dependent protein deacetylase. Sirt6 displays deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Sirt6 also deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Sirt6 is important for the modulation of cellular senescence and apoptosis and the maintenance of telomeres and genomic stability [taken from the Universal Protein Resource (UniProt) Q8N6T7].
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Gen-ID
 - 51548
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NCBI Accession
 - NP_057623
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UniProt
 - Q8N6T7
 
Target
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