NUP98 Antikörper (AA 1650-1700)

Produktnummer ABIN7452380

Der Kaninchen Polyklonal Anti-NUP98-Antikörper wurde für IP validiert. Er ist geeignet, NUP98 in Proben von Human zu detektieren.

Kurzübersicht für NUP98 Antikörper (AA 1650-1700) (ABIN7452380)

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP98 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-NUP98 Antikörper

Bindungsspezifität: AA 1650-1700

Verwendungszweck: Rabbit anti-NUP96 Antibody, Affinity Purified

Homologie: Mouse,Rat

Aufreinigung: Affinity Purified

Immunogen: between AA 1650 and 1700

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-NUP96 antibody ABIN7451910.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NUP98

Target: NUP98 (Nucleoporin 98kDa (NUP98))

Andere Bezeichnung: NUP96

Hintergrund: Background: The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. There are about 30 different human Nups that have been identified. Nup98 is a 98 kDa protein generated from a 186 kDa precursor. The proteolytic cleavage of the 186 kDa precursor also results in a 96 kDa nucleoporin, Nup96. Nup98 and Nup96 have been shown to interact with each other and both play a role in bidirectional transport across the NPC. The NUP98 gene localizes to tumor-suppressor region associated with several types of cancer.

Gen-ID: 4928

NCBI Accession: NP_057404

UniProt: P52948

Pathways: Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interaktom