FKBP5 Antikörper (AA 225-275)
Kurzübersicht für FKBP5 Antikörper (AA 225-275) (ABIN7452330)
Target
Alle FKBP5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 225-275
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Verwendungszweck
- Rabbit anti-FKBP5/FKBP51 Antibody, Affinity Purified
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Homologie
- Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 225 and 275
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Isotyp
- IgG
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anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibody
FKBP5 Reaktivität: Human WB, IF, IHC (p) Wirt: Maus Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 308-457) antibodyFKBP5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) antibodyFKBP5 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibodyFKBP5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibodyFKBP5 Reaktivität: Human WB, IF, ELISA Wirt: Maus Monoclonal 3D1-1B10 unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 1-457) antibodyFKBP5 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3D10-1G11 unconjugated
anti-FK506 Binding Protein 5 (FKBP5) antibodyFKBP5 Reaktivität: Human WB, IF, ICC Wirt: Maus Monoclonal Hi51B unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 2-457) antibodyFKBP5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 201-300) antibodyFKBP5 Reaktivität: Maus, Ratte ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-FK506 Binding Protein 5 (FKBP5) (AA 326-375) antibodyFKBP5 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Hamster, Rind (Kuh), Pferd, Meerschweinchen, Schwein, Zebrafisch (Danio rerio), Fledermaus, Huhn, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-FKBP5/FKBP51 antibody A301-430A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- FKBP5 (FK506 Binding Protein 5 (FKBP5))
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Andere Bezeichnung
- FKBP5/FKBP51
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Hintergrund
- Background: FKBP5/FKBP51 is an immunophilin and target of FK506, a macrolide immunosuppressive drug derived from Streptomyces tsukubaensis. Like other FK506 binding proteins, FKBP5/FKBP51 exhibits peptidyl-prolyl cis-trans isomerase activity. The most studied role of FKBP5/FKBP51 surrounds its involvement in the regulation of steroid receptor signaling. In association with the molecular chaperones Hsp90 and Hsp70, FKBP5/FKBP51 is able to influence steroid-hormone binding affinity and transcriptional activity. Recently, FKBP5/FKBP51 has become of interest in the field of psychiatry due to its potential role in cortisol regulation and its relation to mood disorders.
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Gen-ID
- 2289
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NCBI Accession
- NP_004108
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UniProt
- Q13451
Target
-
