RNF169 Antikörper (AA 200-250)

Produktnummer ABIN7452249

Dieses Anti-RNF169-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RNF169 in IP. Geeignet für Human.

Kurzübersicht für RNF169 Antikörper (AA 200-250) (ABIN7452249)

Target: RNF169 (Ring Finger Protein 169 (RNF169))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF169 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-RNF169 Antikörper

Bindungsspezifität: AA 200-250

Verwendungszweck: Rabbit anti-RNF169 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 200 and 250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452249 has not performed satisfactorily when used for WB of RNF169 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RNF169.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu RNF169

Target: RNF169 (Ring Finger Protein 169 (RNF169))

Andere Bezeichnung: RNF169

Hintergrund: Background: RING finger protein 169 (RNF169) is a probable E3 ubiquitin-protein ligase that acts as a negative regulator of the repair of double-strand breaks (DSBs) following DNA damage. RNF169 is recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSB repair [taken from the Universal Protein Resource (UniProt) Q8NCN4].

Gen-ID: 254225

NCBI Accession: NP_001092108

UniProt: Q8NCN4