RNF169 Antikörper (AA 200-250)
Kurzübersicht für RNF169 Antikörper (AA 200-250) (ABIN7452249)
Target
Alle RNF169 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 200-250
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Verwendungszweck
- Rabbit anti-RNF169 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 200 and 250
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Isotyp
- IgG
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anti-Ring Finger Protein 169 (RNF169) antibody
RNF169 Reaktivität: Human, Ratte, Maus WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 169 (RNF169) (AA 643-742) antibodyRNF169 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Ring Finger Protein 169 (RNF169) (AA 643-742) antibodyRNF169 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3B6 unconjugated
anti-Ring Finger Protein 169 (RNF169) (AA 215-264) antibodyRNF169 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Fledermaus, Huhn, Schwein, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 169 (RNF169) (N-Term) antibodyRNF169 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7452249 has not performed satisfactorily when used for WB of RNF169 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RNF169.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RNF169 (Ring Finger Protein 169 (RNF169))
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Andere Bezeichnung
- RNF169
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Hintergrund
- Background: RING finger protein 169 (RNF169) is a probable E3 ubiquitin-protein ligase that acts as a negative regulator of the repair of double-strand breaks (DSBs) following DNA damage. RNF169 is recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSB repair [taken from the Universal Protein Resource (UniProt) Q8NCN4].
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Gen-ID
- 254225
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NCBI Accession
- NP_001092108
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UniProt
- Q8NCN4
Target
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