WNK1 Antikörper (AA 1625-1675)

Produktnummer ABIN7452167

Der Kaninchen Polyklonal Anti-WNK1-Antikörper wurde für WB und IP validiert. Er ist geeignet, WNK1 in Proben von Human zu detektieren.

Kurzübersicht für WNK1 Antikörper (AA 1625-1675) (ABIN7452167)

Target: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-WNK1 Antikörper

Bindungsspezifität: AA 1625-1675

Verwendungszweck: Rabbit anti-WNK1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1625 and 1675

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu WNK1

Target: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Andere Bezeichnung: WNK1

Hintergrund: Background: WNK1 (with no lysine 1) is a member of the WNK family of serine-threonine kinases. The WNK family of kinases has been observed to play a role in several cellular processes which include ion balance, signal transduction, survival, proliferation and organ development. WNK1 appears to be important to ion homeostasis. Mutations in WNK1 cause pseudohypoaldosteronism type II (PHA II), also called Gordon's syndrome, an autosomal dominant disease characterized by defects in ion transport in the nephron that result in hypertension and hyperkalemia. WNK1 has been reported to regulate sodium and chloride ion transport by influencing the activity of another WNK family member, WNK4. WNKF1 has also been observed to regulate ion homeostasis independent of WNK4.

Gen-ID: 65125

NCBI Accession: NP_061852

UniProt: Q9H4A3