TRIM25 Antikörper (AA 375-425)

Produktnummer ABIN7452118

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIM25 in WB und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRIM25 Antikörper (AA 375-425) (ABIN7452118)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-TRIM25 Antikörper

Bindungsspezifität: AA 375-425

Verwendungszweck: Rabbit anti-TRIM25 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 375 and 425

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25

Hintergrund: Background: TRIM (tripartite motif) proteins, also known as RBCC (RING, B-box, coiled-coil) proteins, are defined by the presence of a tripartite structural motif composed of a RING domain, one or two B-box motifs, and a coiled-coil region. TRIM proteins have been found to be involved in a variety of cellular processes such as apoptosis, proliferation, differentiation, and innate immunity. Of these processes, the most intriguing is their involvement in the innate immune response. TRIM25 has been demonstrated to mediate ubiquitination of the cytosolic receptor retinoic acid-inducible gene-I (RIG-I) in response to viral infection.

Gen-ID: 7706

NCBI Accession: NP_005073

UniProt: Q14258