TLK1 Antikörper (AA 716-766)
Kurzübersicht für TLK1 Antikörper (AA 716-766) (ABIN7452103)
Target
Alle TLK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 716-766
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Verwendungszweck
- Rabbit anti-TLK1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 716 and 766
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- TLK1 (Tousled-Like Kinase 1 (TLK1))
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Andere Bezeichnung
- TLK1
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Hintergrund
- Background: Tousled-like kinase 1 (TLK1) is a serine/threonine kinase involved in chromatin assembly and the DNA damage response. The tousled (Tsl) kinase was first identified in Arabidopsis thaliana and speculated to be involved in cell division during patterning of plant organs. There are two tousled-like kinases in humans, TLK1 and TLK2, that can dimerize or heterodimerize for function and can be phosphorylated and inactivated by Chk1 in response to DNA damage. The histone chaperone, Asf1 (anti-silencing function 1), has been reported as a substrate for both TLK1 and TLK2. TLK1 has also been shown to be important for cell cycle progression and proper chromosome segregation.
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Gen-ID
- 9874
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NCBI Accession
- NP_036422
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UniProt
- Q9UKI8
Target
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