SUZ12 Antikörper (AA 689-739)
Kurzübersicht für SUZ12 Antikörper (AA 689-739) (ABIN7452078)
Target
Alle SUZ12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 689-739
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Verwendungszweck
- Rabbit anti-SUZ12 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 689 and 739
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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Andere Bezeichnung
- SUZ12
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Hintergrund
- Background: SUZ12 (suppressor of zeste 12) is the human homolog of the drosophila SUZ12 gene. SUZ12 is a Polycomb group (PcG) protein and a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. A chromosomal aberration, t(7,17)(p15,q21), involving SUZ12 and JAZF1 may be a cause of endometrial stromal tumors. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer [taken from the Universal Protein Resource (UniProt) Q15022].
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Gen-ID
- 23512
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NCBI Accession
- NP_056170
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UniProt
- Q15022
Target
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