SRA1 Antikörper (C-Term)

Produktnummer ABIN7452064

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SRA1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SRA1 Antikörper (C-Term) (ABIN7452064)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-SRA1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-SRA Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 180 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Andere Bezeichnung: SRA

Hintergrund: Background: Steroid receptor RNA activator 1 (SRA) was originally identified as a functional non-coding RNA that has been shown to be a coactivator of steroid receptors for androgens (AR), estrogens (ER), glucocorticoids, and progestins (PR). SRA exists in ribonucleoprotein complexes with steroid receptor coactivators (SRCs) and steroid receptors and may modulate transcriptional specificity. A 236 amino-acid protein encoded by an SRA-RNA isoform has also been identified. The SRA protein (SRAP) is widely expressed in breast cancer cell lines and breast cancer and has been demonstrated to modify the activity of the estrogen receptor.

Gen-ID: 10011

NCBI Accession: NP_001030312

UniProt: Q9HD15

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development