NCOR2 Antikörper (AA 1525-1575)
Kurzübersicht für NCOR2 Antikörper (AA 1525-1575) (ABIN7452053)
Target
Alle NCOR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1525-1575
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Verwendungszweck
- Rabbit anti-SMRT Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1525 and 1575
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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Andere Bezeichnung
- SMRT
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Hintergrund
- Background: SMRT (silencing mediator of retinoid and thyroid hormone receptor) mediates gene repression by interacting with nuclear receptors such as the thyroid hormone receptor, retinoic acid receptor, progesterone receptor, androgen receptor, estrogen receptor, and glucocorticoids receptor. SMRT mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures.
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Gen-ID
- 9612
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UniProt
- Q9Y618
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Pathways
- Notch Signalweg, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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