ORC1 Antikörper (AA 811-861)

Produktnummer ABIN7451914

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ORC1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ORC1 Antikörper (AA 811-861) (ABIN7451914)

Target: ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-ORC1 Antikörper

Bindungsspezifität: AA 811-861

Verwendungszweck: Rabbit anti-ORC1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 811 and 861

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu ORC1

Target: ORC1 (ORC1L) (Origin Recognition Complex, Subunit 1 (ORC1L))

Andere Bezeichnung: ORC1

Hintergrund: Background: ORC1 (origin recognition complex, subunit 1) is one of six subunits that make up the origin of recognition complex (ORC). The ORC serves as a scaffold for proteins involved in the initiation of DNA replication. Very recently, ORC1 has been found to perform a function independent of its role in DNA replication. In a screen using siRNAs for human ORC proteins to assess their roles in centrosome biology, it was found that ORC1 plays a key role in controlling centriole and centrosome copy number in human cells. ORC1 is also known as replication control protein 1, ORC1L, HSORC1, and PARC1.

Gen-ID: 4998

NCBI Accession: NP_004144

UniProt: Q13415

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA