Mahogunin RING Finger Protein 1 Antikörper (AA 400-450)
Kurzübersicht für Mahogunin RING Finger Protein 1 Antikörper (AA 400-450) (ABIN7451872)
Target
Alle Mahogunin RING Finger Protein 1 (MGRN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-450
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Verwendungszweck
- Rabbit anti-MGRN1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 400 and 450
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Isotyp
- IgG
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anti-Mahogunin, Ring Finger 1 (MGRN1) antibody
MGRN1 Reaktivität: Human, Affe WB, IF, FACS Wirt: Maus Monoclonal 3C3 unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 1-576) antibodyMGRN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 477-576) antibodyMGRN1 Reaktivität: Human WB, IF, ELISA Wirt: Maus Monoclonal 3E1 unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 1-576) antibodyMGRN1 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (AA 252-301) antibodyMGRN1 Reaktivität: Human, Maus, Ratte, Ziege, Meerschweinchen, Affe, Zebrafisch (Danio rerio), Huhn WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mahogunin, Ring Finger 1 (MGRN1) (Middle Region) antibodyMGRN1 Reaktivität: Human, Maus, Ratte, Ziege, Meerschweinchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
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Andere Bezeichnung
- MGRN1
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Hintergrund
- Background: MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) O60291].
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Gen-ID
- 23295
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NCBI Accession
- NP_001135761
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UniProt
- O60291
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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