EIF3H Antikörper (AA 302-352)
Kurzübersicht für EIF3H Antikörper (AA 302-352) (ABIN7451759)
Target
Alle EIF3H Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 302-352
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Verwendungszweck
- Rabbit anti-eIF3H/EIF3S3 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 302 and 352
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
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Andere Bezeichnung
- eIF3H/EIF3S3
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Hintergrund
- Background: Eukaryotic initiation factor 3 subunit H (eIF3H) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5'-end of cellular mRNAs near the cap structure (m7GpppN). eIF3H is a non-conserved subunit and part of the functional core of eIF3. It may function to stabilize the eIF3 complex and stimulate protein synthesis. Many cancer cell lines have been shown to express high levels of eIF3H, and it may have an oncogenic role in colorectal cancer susceptibility.
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Gen-ID
- 8667
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NCBI Accession
- NP_003747
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UniProt
- O15372
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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