ASXL2 Antikörper (AA 600-650)
Kurzübersicht für ASXL2 Antikörper (AA 600-650) (ABIN7451647)
Target
Alle ASXL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 600-650
-
Verwendungszweck
- Rabbit anti-ASXL2 Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 600 and 650
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- ASXL2 (Additional Sex Combs Like 2 (ASXL2))
-
Andere Bezeichnung
- ASXL2
-
Hintergrund
- Background: The gene that encodes Additional sex combs-like protein 2 (ASXL2) is a homolog of the drosophila additional sex combs (Asx) gene. Drosophila Asx is in a class of proteins known as ETP (enhancers of trithorax and polycomb). ETP proteins regulate polycomb-group (PcG) and trithorax-group (trxG) proteins which function to modify the methylation of histones and structure of chromatin. Mutations in ASXL1 are implicated in the development of myelodysplastic syndromes (MDS), a group of hematological diseases characterized by ineffective hematopoiesis and a predisposition to acute myeloid leukemia (AML).
-
Gen-ID
- 55252
-
NCBI Accession
- NP_060733
-
UniProt
- Q76L83
-
Pathways
- Positive Regulation of fat Cell Differentiation
Target
-