Erythrocyte Ankyrin Antikörper (AA 1831-1881)
Kurzübersicht für Erythrocyte Ankyrin Antikörper (AA 1831-1881) (ABIN7451632)
Target
Alle Erythrocyte Ankyrin (ANK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1831-1881
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Verwendungszweck
- Rabbit anti-Ankyrin 1 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1831 and 1881
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
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Andere Bezeichnung
- Ankyrin 1
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Hintergrund
- Background: Ankyrin 1 is a member of the ankyrin family of proteins that function to link integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Ankyrin 1 was first discovered in erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis [taken from NCBI Entrez Gene (Gene ID: 286].
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Gen-ID
- 286
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NCBI Accession
- NP_065209
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UniProt
- P16157
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Pathways
- Synaptic Membrane
Target
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