NIPBL Antikörper (AA 550-600)
Kurzübersicht für NIPBL Antikörper (AA 550-600) (ABIN7451484)
Target
Alle NIPBL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 550-600
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Verwendungszweck
- Rabbit anti-NIPBL Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 550 and 600
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- NIPBL (Nipped-B like Protein (NIPBL))
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Andere Bezeichnung
- NIPBL
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Hintergrund
- Background: The NIPBL (Nipped B-like) gene was originally identified as a gene mutated in individuals with Cornelia de Lange syndrome (CdLS), a heterogenous developmental disorder associated with multiple anatomical malformations. The NIPBL protein product is also referred to as delangin. It has substantial homology to the D. melanogaster Nipped-B protein which is related to a family of chromosomal adherins that plays a role in sister chromatid adhesion, chromosome condensation, and DNA repair. A study of metaphase spreads from individuals positive and negative for NIPBL mutations revealed an association between NIPBL mutations and precocious sister chromatid separation. This result suggests a function for NIPBL that is similar to its homolog in drosophila.
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Gen-ID
- 25836
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NCBI Accession
- NP_597677
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UniProt
- Q6KC79
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Pathways
- Sensory Perception of Sound, Stem Cell Maintenance
Target
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