Multidrug-Resistance Like Protein 1 Antikörper (AA 275-325)

Produktnummer ABIN7451476

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Multidrug-Resistance Like Protein 1 in IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Multidrug-Resistance Like Protein 1 Antikörper (AA 275-325) (ABIN7451476)

Target: Multidrug-Resistance Like Protein 1 (MRP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Multidrug-Resistance Like Protein 1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-Multidrug-Resistance Like Protein 1 Antikörper

Bindungsspezifität: AA 275-325

Verwendungszweck: Rabbit anti-MRP1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 275 and 325

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Multidrug-Resistance Like Protein 1

Target: Multidrug-Resistance Like Protein 1 (MRP)

Andere Bezeichnung: MRP1

Hintergrund: Background: Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. MRP1 functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. MRP1 also transports glucuronides and sulfate conjugates of steroid hormones and bile salts [taken from NCBI Entrez Gene (Gene ID: 4363)].

Gen-ID: 4363

NCBI Accession: NP_004987

UniProt: P33527