RBBP6 Antikörper (AA 900-950)
Kurzübersicht für RBBP6 Antikörper (AA 900-950) (ABIN7451322)
Target
Alle RBBP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 900-950
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Verwendungszweck
- Rabbit anti-RBBP6 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 900 and 950
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-RBBP6 antibody ABIN7450638.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
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Andere Bezeichnung
- RBBP6
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Hintergrund
- Background: Retinoblastoma-binding protein 6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). RBBP3 may play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53. It may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity) [taken from the Universal Protein Resource (UniProt) Q7Z6E9].
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Gen-ID
- 5930
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UniProt
- Q7Z6E9
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Pathways
- Regulatorische RNA Pathways
Target
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