Cadherin 13 Antikörper (AA 475-525)

Produktnummer ABIN7451103

Dieses Anti-Cadherin 13-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cadherin 13 in IP. Geeignet für Human.

Kurzübersicht für Cadherin 13 Antikörper (AA 475-525) (ABIN7451103)

Target: Cadherin 13 (CDH13)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 13 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-Cadherin 13 Antikörper

Bindungsspezifität: AA 475-525

Verwendungszweck: Rabbit anti-Cadherin 13/CDH13/T-cadherin Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 475 and 525

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451103 has not performed satisfactorily when used for WB of Cadherin 13/CDH13/T-cadherin in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Cadherin 13/CD.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Cadherin 13

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: Cadherin 13/CDH13/T-cadherin

Hintergrund: Background: Cadherin-13 is a member of the cadherin superfamily. Cadherin-13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. Cadherin-13 lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. Cadherin-13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis [taken from NCBI Entrez Gene (Gene ID: 1012)].

Gen-ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization