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MDC1 Antikörper (AA 900-950)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MDC1 in IP. Er zeigt eine Reaktivität gegenüber Maus.

Produktnummer ABIN7451086

Kurzübersicht für MDC1 Antikörper (AA 900-950) (ABIN7451086)

Target

Alle MDC1 Antikörper anzeigen

MDC1 (Mdc1 (MDC1))

Reaktivität

60
43
16
12
11
2
1
1

Maus

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

28
6
6
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

Dieser MDC1 Antikörper ist unkonjugiert

Applikation

58
22
14
13
13
13
12
10
9
5
3
2
1
1
1

Immunoprecipitation (IP)

Discover our top product MDC1 Primärantikörper

Bindungsspezifität
21

15

10

8

5

3

2

2

2

1

1

1

1

1

1

1

1
AA 900-950

Verwendungszweck

Rabbit anti-Mdc1/Nfbd1 Antibody, Affinity Purified

Aufreinigung

Affinity Purified

Immunogen

Between AA 900 and 950

Isotyp

IgG
anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Mdc1 (MDC1) antibody
MDC1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 31-130) antibody
MDC1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 1-350) antibody
MDC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody
MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody (HRP)
MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 HRP

anti-Mdc1 (MDC1) (N-Term) antibody (FITC)
MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 FITC

anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)
MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Biotin

anti-Mdc1 (MDC1) (N-Term) antibody (PE)
MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 PE

anti-Mdc1 (MDC1) (N-Term) antibody (APC)
MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 APC

Applikationshinweise

IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451086 has not performed satisfactorily when used for WB of Mdc1/Nfbd1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Mdc1/Nfbd1.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1000 μg/mL

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Haltbarkeit

12 months
Target

MDC1 (Mdc1 (MDC1))

Andere Bezeichnung

Mdc1/Nfbd1

Hintergrund

Background: Mediator of DNA damage checkpoint protein 1 (Mdc1) is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. It is also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis [taken from the Universal Protein Resource (UniProt) Q5PSV9].

Gen-ID

240087

NCBI Accession

NP_001010833

UniProt

Q5PSV9

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