NSMCE2 Antikörper (AA 197-247)
Kurzübersicht für NSMCE2 Antikörper (AA 197-247) (ABIN7451060)
Target
Alle NSMCE2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 197-247
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Verwendungszweck
- Rabbit anti-MMS21 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 197 and 247
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451060 has not performed satisfactorily when used for WB of MMS21 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MMS21.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
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Andere Bezeichnung
- MMS21
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Hintergrund
- Background: The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) Q96MF7].
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Gen-ID
- 286053
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NCBI Accession
- NP_775956
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UniProt
- Q96MF7
Target
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