PURB Antikörper (AA 262-312)

Produktnummer ABIN7451054

Der Kaninchen Polyklonal Anti-PURB-Antikörper wurde für IP validiert. Er ist geeignet, PURB in Proben von Human zu detektieren.

Kurzübersicht für PURB Antikörper (AA 262-312) (ABIN7451054)

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PURB Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-PURB Antikörper

Bindungsspezifität: AA 262-312

Verwendungszweck: Rabbit anti-Pur-beta Antibody, Affinity Purified

Homologie: Mouse,Rat

Aufreinigung: Affinity Purified

Immunogen: Between AA 262 and 312

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451054 has not performed satisfactorily when used for WB of Pur-beta in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Pur-beta.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PURB

Target: PURB (Purine-Rich Element Binding Protein B (PURB))

Andere Bezeichnung: Pur-beta

Hintergrund: Background: Pur-beta (purine-rich element binding protein B) is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the Pur-beta gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia [taken from NCBI Entrez Gene (Gene ID: 5814)].

Gen-ID: 5814

NCBI Accession: NP_150093

UniProt: Q96QR8