UBQLN4 Antikörper (AA 1-50)
Kurzübersicht für UBQLN4 Antikörper (AA 1-50) (ABIN7450868)
Target
Alle UBQLN4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotyp
- IgG
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anti-Ubiquilin 4 (UBQLN4) (AA 300-390) antibody
UBQLN4 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 1-30), (N-Term) antibodyUBQLN4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB43631 unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 287-336) antibodyUBQLN4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Schwein, Affe, Huhn, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 201-250) antibodyUBQLN4 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (Middle Region) antibodyUBQLN4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Hund, Schwein, Schaf WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (N-Term) antibodyUBQLN4 Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- UBQLN4 (Ubiquilin 4 (UBQLN4))
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Andere Bezeichnung
- UBQLN4/CIP75/Ubiquilin 4
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Hintergrund
- Background: Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
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Gen-ID
- 56893
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UniProt
- Q9NRR5
Target
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