Stanniocalcin 2 Antikörper (AA 252-302)

Produktnummer ABIN7450781

Der Kaninchen Polyklonal Anti-Stanniocalcin 2-Antikörper wurde für WB und IP validiert. Er ist geeignet, Stanniocalcin 2 in Proben von Human zu detektieren.

Kurzübersicht für Stanniocalcin 2 Antikörper (AA 252-302) (ABIN7450781)

Target: Stanniocalcin 2 (STC2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stanniocalcin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Stanniocalcin 2 Antikörper

Bindungsspezifität: AA 252-302

Verwendungszweck: Rabbit anti-Stanniocalcin 2 Antibody, Affinity Purified

Homologie: Mouse,Rat,Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 252 and 302

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Stanniocalcin 2

Target: Stanniocalcin 2 (STC2)

Andere Bezeichnung: Stanniocalcin 2

Hintergrund: Background: Stanniocalcin 2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. Stanniocalcin 2 may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and is altered in some breast cancers [taken from NCBI Entrez Gene (GeneID: 8614)].

Gen-ID: 8614

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interaktom