SHARPIN Antikörper (AA 25-75)
Kurzübersicht für SHARPIN Antikörper (AA 25-75) (ABIN7450727)
Target
Alle SHARPIN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 25-75
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Verwendungszweck
- Rabbit anti-SHARPIN Antibody, Affinity Purified
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Homologie
- Bovine
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 25 and 75
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SHARPIN (SHANK-Associated RH Domain Interacting Protein (SHARPIN))
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Andere Bezeichnung
- SHARPIN
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Hintergrund
- Background: Sharpin (Shank-associated RH domain-interacting protein) is a component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways [taken from the Universal Protein Resource (UniProt) Q9H0F6].
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Gen-ID
- 81858
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NCBI Accession
- NP_112236
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UniProt
- Q9H0F6
Target
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