SH3BP2 Antikörper (AA 150-200)
Kurzübersicht für SH3BP2 Antikörper (AA 150-200) (ABIN7450726)
Target
Alle SH3BP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 150-200
-
Verwendungszweck
- Rabbit anti-SH3BP2 Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 150 and 200
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
-
Andere Bezeichnung
- SH3BP2
-
Hintergrund
- Background: SH3 domain-binding protein 2 (SH3BP2) N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism, an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws followed by development of fibrous tissue masses and characteristic facial swelling [taken from NCBI Entrez Gene (Gene ID: 6452)].
-
Gen-ID
- 6452
-
NCBI Accession
- NP_001116153
-
UniProt
- P78314
-
Pathways
- T-Zell Rezeptor Signalweg
Target
-