PYGL Antikörper (AA 797-847)
Kurzübersicht für PYGL Antikörper (AA 797-847) (ABIN7450622)
Target
Alle PYGL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 797-847
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Verwendungszweck
- Rabbit anti-PYGL Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 797 and 847
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PYGL (phosphorylase, Glycogen, Liver (PYGL))
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Andere Bezeichnung
- PYGL
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Hintergrund
- Background: Glycogen phosphorylase, liver form, (PYGL) encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues [taken from NCBI Entrez Gene (Gene ID: 5836)].
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Gen-ID
- 5836
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NCBI Accession
- NP_002854
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UniProt
- P06737
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Pathways
- Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
Target
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