PATL1 Antikörper (AA 425-475)

Produktnummer ABIN7450546

Produktdetails anti-PATL1 Antikörper

Target: PATL1 (Protein Associated with Topoisomerase II Homolog 1 (PATL1))

Bindungsspezifität: AA 425-475

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PATL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-Pat1b Antibody, Affinity Purified

Homologie: Mouse,Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 425 and 475

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PATL1

Target: PATL1 (Protein Associated with Topoisomerase II Homolog 1 (PATL1))

Andere Bezeichnung: Pat1b (PATL1 Produkte)

Synonyme: Pat1b antikoerper, xPat1b antikoerper, hPat1b antikoerper, AV312086 antikoerper, D430024J04 antikoerper, RGD1305514 antikoerper, fa11d04 antikoerper, wu:fa11d04 antikoerper, zgc:158239 antikoerper, PAT1 homolog 1, processing body mRNA decay factor antikoerper, protein associated with topoisomerase II homolog 1 L homeolog antikoerper, protein associated with topoisomerase II homolog 1 (yeast) antikoerper, PATL1 antikoerper, patl1.L antikoerper, Patl1 antikoerper, patl1 antikoerper

Hintergrund: Background: Pat1 homolog b (Pat1b) is an RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Pat1b acts as a scaffold protein that connects deadenylation and decapping machinery. Pat1b is required for cytoplasmic mRNA processing body (P-body) assembly, and in cases of infection, it is required for translation and replication of hepatitis C virus (HCV) [taken from the Universal Protein Resource (UniProt) Q86TB9].

Gen-ID: 219988

NCBI Accession: NP_689929

UniProt: Q86TB9

Pathways: Ribonucleoprotein Complex Subunit Organization