PAPD1 Antikörper (AA 532-582)

Produktnummer ABIN7450541

Produktdetails anti-PAPD1 Antikörper

Target: PAPD1 (MTPAP) (Mitochondrial Poly(A) Polymerase (MTPAP))

Bindungsspezifität: AA 532-582

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-PAPD1 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 532 and 582

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PAPD1

Target: PAPD1 (MTPAP) (Mitochondrial Poly(A) Polymerase (MTPAP))

Andere Bezeichnung: PAPD1 (MTPAP Produkte)

Synonyme: PAPD1 antikoerper, SPAX4 antikoerper, 0610027A18Rik antikoerper, AW551379 antikoerper, Papd1 antikoerper, mitochondrial poly(A) polymerase antikoerper, MTPAP antikoerper, Mtpap antikoerper

Hintergrund: Background: PAPD1 (mitochondrial poly(A) polymerase) is a polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. PAPD1 can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). It plays a role in replication-dependent histone mRNA degradation. It may be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated and might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA [taken from NCBI Entrez Gene (Gene ID: 55149)].

Gen-ID: 55149

NCBI Accession: NP_060579

UniProt: Q9NVV4