Junctophilin 2 Antikörper (AA 625-675)
Kurzübersicht für Junctophilin 2 Antikörper (AA 625-675) (ABIN7450382)
Target
Alle Junctophilin 2 (JPH2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 625-675
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Verwendungszweck
- Rabbit anti-Junctophilin-2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 625 and 675
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Junctophilin 2 (JPH2)
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Andere Bezeichnung
- Junctophilin-2
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Hintergrund
- Background: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Junctophilins provide a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. Junctophilin-2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release, and contributes to the construction of skeletal muscle triad junctions [taken from the Universal Protein Resource (UniProt) Q9BR39].
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Gen-ID
- 57158
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NCBI Accession
- NP_065166
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UniProt
- Q9BR39
Target
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