ISR-beta Antikörper (AA 1332-1382)
Kurzübersicht für ISR-beta Antikörper (AA 1332-1382) (ABIN7450366)
Target
Alle ISR-beta Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1332-1382
-
Verwendungszweck
- Rabbit anti-Insulin Receptor Beta Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- Between AA 1332 and 1382
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- ISR-beta (Insulin Receptor beta (ISR-beta))
-
Andere Bezeichnung
- Insulin Receptor Beta
-
Hintergrund
- Background: The insulin receptor is a receptor tyrosine kinase that mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates to stimulate uptake of glucose. The insulin receptor is synthesized as a single polypeptide that is cleaved to generate an alpha and beta subunit. The subunit structure of the insulin receptor consists of a tetramer of two alpha and two beta chains linked by disulfide bonds.
-
Gen-ID
- 3643
-
NCBI Accession
- NP_000199
-
UniProt
- P06213
Target
-