ERBB2IP Antikörper (AA 825-875)
Kurzübersicht für ERBB2IP Antikörper (AA 825-875) (ABIN7450219)
Target
Alle ERBB2IP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 825-875
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Verwendungszweck
- Rabbit anti-Erbin Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 825 and 875
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))
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Andere Bezeichnung
- Erbin
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Hintergrund
- Background: Erbin (Erbb2-interacting protein) is a member of the leucine-rich repeat and PDZ domain (LAP) family. Erbin contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction [taken from NCBI Entrez Gene (Gene ID: 55914)].
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Gen-ID
- 55914
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UniProt
- Q96RT1
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Pathways
- EGFR Signaling Pathway, Asymmetric Protein Localization
Target
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