Cyclin L2 Antikörper (AA 470-520)

Produktnummer ABIN7450148

Der Kaninchen Polyklonal Anti-Cyclin L2-Antikörper wurde für WB und IP validiert. Er ist geeignet, Cyclin L2 in Proben von Human zu detektieren.

Kurzübersicht für Cyclin L2 Antikörper (AA 470-520) (ABIN7450148)

Target: Cyclin L2 (CCNL2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Cyclin L2 Antikörper

Bindungsspezifität: AA 470-520

Verwendungszweck: Rabbit anti-Cyclin L2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 470 and 520

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Cyclin L2

Target: Cyclin L2 (CCNL2)

Andere Bezeichnung: Cyclin L2

Hintergrund: Background: Cyclin L2 is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression and transcription. The hallmark characteristic of cyclins is the periodicity of their expression and activity that is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin L2 is part of a group of cyclins that are involved in transcriptional regulation at the level of RNA transcription, initiation, elongation, and RNA processing. The transcriptional regulating cyclins include cyclin C, H, K, L1, L2, T1, and T2 which associate with CDK7, -8, -9, -10 and -12. Cyclin L2 associates with CDK11 and RNA polymerase II and co-localizes with splicing factors and is implicated to play a role in pre-mRNA splicing.

Gen-ID: 81669

NCBI Accession: NP_112199

UniProt: Q96S94