CDK13 Antikörper (AA 1125-1175)

Produktnummer ABIN7450096

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CDK13 in WB und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CDK13 Antikörper (AA 1125-1175) (ABIN7450096)

Target: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-CDK13 Antikörper

Bindungsspezifität: AA 1125-1175

Verwendungszweck: Rabbit anti-CDC2L5 Antibody, Affinity Purified

Homologie: Mouse,Bovine

Aufreinigung: Affinity Purified

Immunogen: between AA 1125 and 1175

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CDK13

Target: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Andere Bezeichnung: CDC2L5

Hintergrund: Background: CDC2-like kinase 5 (CDC2L5) is a member of the cyclin-dependent serine/threonine protein kinase family that plays a central role in cell cycle control. The CDC2L5 cDNA was first identified as CHED (cholinesterase-related cell-division controller) and cloned serendipitously in a screen using a cholinesterase-specific oligonucleotide probe in search of a link between cholinergic signaling and hematopoietic cell division control. Recently, the understanding of the physiological function of CDC2L5 has become clearer. Due to its localization to speckles in the nucleoplasm and its interaction with the splicing protein, ASF/SF2-associated protein p32, it was suggested to play a role in mRNA processing. Further studies showed that overexpression of CDC2L5 altered mRNA splicing patterns, and that CDC2L5 associated with L-type cyclins known to be involved in alternative splicing. These results have led to the conclusion that CDC2L5 is part of a subfamily of cyclin dependent kinases that play a role in the regulation of alternative splicing.

Gen-ID: 8621

NCBI Accession: NP_003709

UniProt: Q14004