MCAM Antikörper (AA 600-650)
Kurzübersicht für MCAM Antikörper (AA 600-650) (ABIN7450088)
Target
Alle MCAM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 600-650
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Verwendungszweck
- Rabbit anti-CD146 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 600 and 650
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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Andere Bezeichnung
- CD146
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Hintergrund
- Background: CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. CD146 could be an adhesion molecule active in neural crest cells during embryonic development. CD146 acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration [taken from the Universal Protein Resource (UniProt) P43121].
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Gen-ID
- 4162
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NCBI Accession
- NP_006491
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UniProt
- P43121
Target
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