SHANK3 Antikörper (AA 1475-1525)
Kurzübersicht für SHANK3 Antikörper (AA 1475-1525) (ABIN7449919)
Target
Alle SHANK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1475-1525
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Verwendungszweck
- Rabbit anti-SHANK3 Antibody, Affinity Purified
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Homologie
- Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1475 and 1525
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
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Andere Bezeichnung
- SHANK3
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Hintergrund
- Background: SH3 and multiple ankyrin repeat domains 3 (SHANK3) seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. SHANK3 may play a role in the structural and functional organization of the dendritic spine and synaptic junction. [taken from the Universal Protein Resource (UniProt) Q9BYB0].
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Gen-ID
- 85358
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NCBI Accession
- NP_277052
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UniProt
- Q9BYB0
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Pathways
- Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
Target
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