MED24 Antikörper (AA 939-989)

Produktnummer ABIN7449847

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MED24 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MED24 Antikörper (AA 939-989) (ABIN7449847)

Target: MED24 (Mediator Complex Subunit 24 (MED24))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-MED24 Antikörper

Bindungsspezifität: AA 939-989

Verwendungszweck: Rabbit anti-TRAP100/MED24 Antibody, Affinity Purified

Homologie: Rat,Chicken

Aufreinigung: Affinity Purified

Immunogen: between AA 939 and 989

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu MED24

Target: MED24 (Mediator Complex Subunit 24 (MED24))

Andere Bezeichnung: TRAP100/MED24

Hintergrund: Background: TRAP100/MED24 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. TRAP100/MED24 associates with mediator subunit TRAP220. Both are essential to mouse development and play a role in androgen receptor-mediated transcription. Studies in zebrafish have shown that TRAP100/MED24 is also important to retinal development.

Gen-ID: 9862

NCBI Accession: NP_055630

UniProt: O75448

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity